With the development of big data, computer classroom teaching in secondary vocational schools is facing unprecedented opportunities and challenges. By exploring the advantages of big data technology in computer classroom teaching in secondary vocational schools (including improving teaching pertinence, enhancing practical operation ability training and broadening access to resources), This paper puts forward some classroom teaching reform strategies based on big data, such as making micro-class video resources, implementing flipped classroom mode, building network teaching platform, improving teaching evaluation system, optimizing classroom teaching mode and integrating cutting-edge technology. It aims to promote the innovation and reform of computer classroom teaching in secondary vocational schools, enhance students learning interest, self-learning ability and practical innovation ability, and adapt to the rapidly changing industry needs.